SCHEMBL1136053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136173	0.91	ALDH1A1 (0.43)	ALDH1A1PKMHPGDTSHRMAPT
	SCHEMBL2427556	0.89	KMT2A (0.39)	ALDH1A1PKMKMT2AMDM2S1PR4
	SCHEMBL2434676	0.89	MAPT (0.37)	ALDH1A1PKMKMT2AMDM2S1PR4
	SCHEMBL1136169	0.83	PTGS2 (0.41)	ALDH1A1PKMCSNK2A1
	SCHEMBL1135964	0.81	MAOB (0.39)	ALDH1A1PKM
	SCHEMBL2427472	0.81	ADRB3 (0.46)	ALDH1A1PKMKMT2AMDM2HPGD
	SCHEMBL1136104	0.81	PDE4D (0.37)	ALDH1A1PKMHPGD
	SCHEMBL1136159	0.80	MAOB (0.36)	ALDH1A1PKM
	SCHEMBL1136374	0.80	EGFR (0.38)	ALDH1A1KMT2AHPGDTSHRMAPT
	SCHEMBL1136199	0.80	PDE4D (0.41)	ALDH1A1PKMKMT2AHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.