Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758552 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL11364358 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL1997012 | 0.71 | MGAM (0.53) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13801139 | 0.71 | ADORA2A (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL11372956 | 0.69 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11374643 | 0.69 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13680728 | 0.69 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EHSD17B10MAPT | |
| SCHEMBL11364788 | 0.69 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL127716 | 0.68 | FBP1 (0.54) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL570555 | 0.68 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265898-A | ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |