Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489458 | 0.95 | L3MBTL1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10MAPK10 | |
| SCHEMBL4482497 | 0.89 | HSP90AA1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL11365725 | 0.77 | CYBB (0.39) | ALDH1A1KDM4EHSD17B10L3MBTL1POLB | |
| SCHEMBL11366454 | 0.71 | PARP1 (0.47) | ALDH1A1KDM4EHSD17B10PARP1MAPK1 | |
| SCHEMBL11362511 | 0.69 | SMN1; SMN2 (0.38) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL21920713 | 0.68 | KDM4E (0.41) | ALDH1A1HPGDKDM4EHSD17B10MAPK10 | |
| SCHEMBL11362227 | 0.68 | GLO1 (0.39) | ALDH1A1KDM4EHSD17B10L3MBTL1HSP90AA1 | |
| SCHEMBL11364424 | 0.68 | GLO1 (0.39) | ALDH1A1HPGDKDM4EL3MBTL1HSP90AA1 | |
| SCHEMBL6493490 | 0.68 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EHSD17B10MAPK10 | |
| Biphenyl SCHEMBL29276701 | 0.65 | NISCH (0.45) | ALDH1A1HPGDKDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288438-A | Nitrogen-containing heterocyclic ring derivatives and analgesic and anti-inflammatory compositions and methods employing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-09-08 | — | — | US | disclosed |
| US-4284778-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4251533-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4186200-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-01-29 | — | — | US | disclosed |