Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873922 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28318666 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11369024 | 0.75 | NOS3 (0.41) | KDM4ESMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL623986 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11368641 | 0.73 | ADORA2A (0.55) | RAB9AMEN1KMT2ANOS1ADORA2A | |
| SCHEMBL11365792 | 0.73 | NPC1 (0.44) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16686134 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30968903 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28151348 | 0.73 | LMNA (0.54) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11373116 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017500-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1977-04-12 | — | — | US | claimed |
| US-4260759-A | CONDENSATION OF NITRILES | SCHERING-CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4115395-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4107166-A | ANTIFUNGAL, ANTIBACTERIAL | SCHERING CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4017500-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |