Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695787 | 0.87 | MAPT (0.74) | MAPTCYP3A4ALOX15TSHRPDE4A | |
| SCHEMBL770139 | 0.83 | ALDH1A1 (0.50) | CYP3A4ALOX15ALDH1A1ALOX5PTGS1 | |
| SCHEMBL14193724 | 0.77 | MAPT (0.60) | MAPTDHFRPDE4APDE4BPDE4C | |
| SCHEMBL8451613 | 0.77 | CYP3A4 (0.51) | CYP3A4ALOX15ALDH1A1ALOX5PTGS1 | |
| SCHEMBL4877224 | 0.76 | GABRA1 (0.60) | MAPTCYP3A4ALDH1A1ALOX5PTGS1 | |
| SCHEMBL1841607 | 0.76 | MAPT (0.65) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17491870 | 0.75 | TNKS (0.54) | MAPTCYP3A4ALOX15ALDH1A1ALOX5 | |
| SCHEMBL9701610 | 0.75 | CYP3A4 (0.44) | CYP3A4ALOX15ALDH1A1ALOX5PTGS1 | |
| SCHEMBL5879482 | 0.75 | CYP3A4 (0.50) | CYP3A4ALOX15ALDH1A1ALOX5PTGS1 | |
| SCHEMBL2687511 | 0.75 | KDM4E (0.45) | MAPTALDH1A1ALOX5DHFRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256844-A | WATERPROOFING; PROTECTIVE COATINGS, FOAM IMPREGNATION; CONSTRUCTION MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4164487-A | SOLVENT-RESISTANT, FLEXIBLE COATINGS | THE DOW CHEMICAL COMPANY (US) | 1979-08-14 | — | — | US | disclosed |