Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594233 | 0.90 | CYP3A4 (0.46) | CYP3A4ALOX15ACHEPOLBALDH1A1 | |
| SCHEMBL8451613 | 0.84 | CYP3A4 (0.51) | CYP3A4ALOX15POLBALDH1A1PPARG | |
| SCHEMBL770139 | 0.83 | ALDH1A1 (0.50) | CYP3A4ALOX15POLBALDH1A1PPARG | |
| SCHEMBL14372999 | 0.82 | KDM4E (0.44) | CYP3A4ALOX15ACHEPOLBALDH1A1 | |
| SCHEMBL16200754 | 0.81 | PTPN1 (0.41) | CYP3A4ALOX15ACHEPOLBALDH1A1 | |
| SCHEMBL14373013 | 0.81 | HSD17B10 (0.41) | CYP3A4ALOX15ALDH1A1PPARASMN1; SMN2 | |
| SCHEMBL25318875 | 0.80 | ACHE (0.47) | CYP3A4ALOX15ACHEPOLBALDH1A1 | |
| SCHEMBL14372984 | 0.80 | KDM4E (0.39) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL16200753 | 0.79 | ALDH1A1 (0.41) | CYP3A4ALOX15POLBALDH1A1PPARG | |
| SCHEMBL44672 | 0.78 | GABRA1 (0.48) | CYP3A4ALOX15POLBALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141684-B2 | Diepoxide derivatives of diallyl phenolics | PEWS R GARTH | 2006-11-28 | — | — | US | disclosed |
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | PEWS R G (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | EBP, EED, ESR2 | CYP3A4 251/4885ALOX15 171/4885ACHE 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.