Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26200949 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL17491870 | 0.87 | TNKS (0.54) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL8451613 | 0.84 | CYP3A4 (0.51) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL11366349 | 0.83 | MAPT (0.59) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL5879482 | 0.83 | CYP3A4 (0.50) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL2462713 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL68542 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL8965460 | 0.81 | FFAR4 (0.49) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL11553231 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG | |
| SCHEMBL31005006 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CYP3A4ALOX15SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060016064-A1 | Medical device including unitary, continuous portion of varying durometer | COOK INCORPORATED AND SABIN CORPORATION | 2006-01-26 | — | — | US | claimed |
| US-6881209-B2 | Medical device including unitary, continuous portion of varying durometer | COOK INCORPORATED (US) | 2005-04-19 | — | — | US | claimed |
| US-20040073164-A1 | Medical device including improved expandable balloon | COOK INCORPORATED | 2004-04-15 | — | — | US | claimed |
| US-20030195490-A1 | Medical device including unitary, continuous portion of varying durometer | COOK INCORPORATED (US) | 2003-10-16 | — | — | US | claimed |
| US-6592550-B1 | Medical device including improved expandable balloon | COOK INCORPORATED | 2003-07-15 | — | — | US | claimed |
| US-20160213891-A1 | Medical Dilation Element | ZAMORE, ALAN | 2016-07-28 | — | — | US | disclosed |
| US-9333278-B2 | Medical dilation element | Medtech Capital Ventures LLC (US) | 2016-05-10 | — | — | US | disclosed |
| US-20120070599-A1 | Reduced profile medical balloon element | ZAMORE, ALAN | 2012-03-22 | — | — | US | disclosed |
| US-8034415-B2 | Formaldehyde-free phenolic resin binder | SAINT-GOBAIN ISOVER (FR) | 2011-10-11 | — | — | US | disclosed |
| US-20100249906-A1 | REDUCED PROFILE MEDICAL BALLOON ELEMENT | ZAMORE ALAN M | 2010-09-30 | — | — | US | disclosed |
| US-20100211024-A1 | Irradiation Conversion of Thermoplastic to Thermoset Polymers | ZAMORE ALAN M | 2010-08-19 | — | — | US | disclosed |
| US-7749585-B2 | Reduced profile medical balloon element | ZAMORE, ALAN | 2010-07-06 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20060016064-A1 | Medical device including unitary, continuous portion of varying durometer | COOK INCORPORATED AND SABIN CORPORATION | 2006-01-26 | — | — | US | disclosed |
| US-6881209-B2 | Medical device including unitary, continuous portion of varying durometer | COOK INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| US-20040093008-A1 | Reduced profile medical balloon element | ZAMORE, ALAN | 2004-05-13 | — | — | US | disclosed |
| US-20040073164-A1 | Medical device including improved expandable balloon | COOK INCORPORATED | 2004-04-15 | — | — | US | disclosed |
| US-20040002729-A1 | Irradiation conversion of thermoplastic to thermoset polymers | ZAMORE, ALAN | 2004-01-01 | — | — | US | disclosed |
| US-20030195490-A1 | Medical device including unitary, continuous portion of varying durometer | COOK INCORPORATED (US) | 2003-10-16 | — | — | US | disclosed |
| US-6592550-B1 | Medical device including improved expandable balloon | COOK INCORPORATED | 2003-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | CCNK, CDK3, CCNO | ALDH1A1 1982/4885CYP3A4 4376/4885ALOX15 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.