Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359711 | 0.75 | TSHR (0.34) | SMN1; SMN2SLC6A3ALDH1A1LMNAMEN1 | |
| SCHEMBL12809631 | 0.74 | TYR (0.43) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL25042522 | 0.69 | DPP4 (0.38) | ALDH1A1LMNAKDM4EHIF1A | |
| SCHEMBL2400000 | 0.66 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30843547 | 0.64 | AKR1C3 (0.36) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20231997 | 0.64 | AKR1C3 (0.36) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3056114 | 0.64 | SLC6A3 (0.47) | SLC6A3ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4054068 | 0.63 | CYP2D6 (0.48) | SLC6A3LMNATSHRCYP3A4MAPK1 | |
| SCHEMBL18029846 | 0.63 | MEN1 (0.41) | SLC6A3LMNAMEN1KMT2ATSHR | |
| SCHEMBL8415522 | 0.61 | SLC6A3 (0.45) | SLC6A3TSHRPTGS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247548-A | 7α-Methoxycephalosporin derivatives and their pharmaceutical compositions having antibacterial activity | SANKYO COMPANY LIMITED (JP) | 1981-01-27 | — | — | US | disclosed |