Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320324 | 0.79 | NPBWR1 (0.42) | TYRSMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL25042522 | 0.79 | DPP4 (0.38) | ALDH1A1LMNAGAABRD4CREBBP | |
| SCHEMBL19879528 | 0.74 | HSD17B10 (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6516730 | 0.72 | TRPA1 (0.37) | — | |
| SCHEMBL20231997 | 0.70 | AKR1C3 (0.36) | SMN1; SMN2KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL31060521 | 0.70 | — | — | |
| SCHEMBL18789965 | 0.70 | — | — | |
| SCHEMBL1755703 | 0.70 | — | — | |
| Hydrogen Peroxide SCHEMBL8846644 | 0.70 | ESR1 (0.55) | TYRKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL7499823 | 0.67 | TAAR1 (0.50) | TYRKMT2ATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201006-B1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2011-03-09 | — | — | EP | disclosed |