Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.34 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056114 | 0.84 | SLC6A3 (0.47) | MEN1KMT2ACYP2D6MAPK1SLC6A3 | |
| SCHEMBL9701512 | 0.73 | L3MBTL1 (0.45) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL1959777 | 0.71 | TSHR (0.46) | MEN1KMT2AALOX5CYP2D6MAPK1 | |
| SCHEMBL2036296 | 0.71 | PTGS1 (0.48) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL2026462 | 0.71 | PTGS1 (0.48) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL12157016 | 0.71 | PTGS1 (0.48) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL9700450 | 0.70 | BRD4 (0.47) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL22749374 | 0.70 | TYR (0.47) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL10442632 | 0.69 | BCL2 (0.40) | MEN1KMT2ANPC1TTRALOX5 | |
| SCHEMBL4054068 | 0.68 | CYP2D6 (0.48) | CYP2D6MAPK1SLC6A3LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351492-B2 | Introduction of alkyl substituents to aromatic compounds | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS (IL) | 2019-07-16 | — | — | US | disclosed |
| US-20180065904-A1 | INTRODUCTION OF ALKYL SUBSTITUENTS TO AROMATIC COMPOUNDS | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2018-03-08 | — | — | US | disclosed |
| US-20180065904-A1 | INTRODUCTION OF ALKYL SUBSTITUENTS TO AROMATIC COMPOUNDS | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2018-03-08 | — | — | US | disclosed |
| WO-2016132355-A1 | INTRODUCTION OF ALKYL SUBSTITUENTS TO AROMATIC COMPOUNDS | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2016-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065904-A1 | INTRODUCTION OF ALKYL SUBSTITUENTS TO AROMATIC COMPOUNDS | TST, NAT1, CBS | MEN1 3203/4885KMT2A 1780/4885NPC1 2349/4885 |
| US-10351492-B2 | Introduction of alkyl substituents to aromatic compounds | TST, NAT1, CBS | MEN1 3203/4885KMT2A 1780/4885NPC1 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.