Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA5A | P35218 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441222 | 0.88 | RPS6KA2 (0.40) | RPS6KA2NPSR1LMNAMAPTPOLB | |
| SCHEMBL11377390 | 0.84 | CYP3A4 (0.44) | RPS6KA2NPSR1LMNAMAPTPOLB | |
| SCHEMBL11367236 | 0.83 | PGR (0.39) | RPS6KA2NPSR1LMNAMAPTPOLB | |
| SCHEMBL11440071 | 0.83 | RPS6KA2 (0.37) | RPS6KA2NPSR1LMNAMAPTPOLB | |
| SCHEMBL11379754 | 0.81 | MAPT (0.40) | RPS6KA2NPSR1LMNAMAPTPOLB | |
| SCHEMBL11375946 | 0.80 | ALOX15 (0.38) | RPS6KA2LMNAMAPTPOLBCA12 | |
| SCHEMBL11374415 | 0.79 | LMNA (0.44) | NPSR1LMNAMAPTPOLBCHRM3 | |
| SCHEMBL11235699 | 0.73 | MAPT (0.34) | RPS6KA2NPSR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11364764 | 0.73 | NPSR1 (0.40) | RPS6KA2NPSR1LMNAMAPTPOLB | |
| SCHEMBL11380867 | 0.71 | PGR (0.37) | NPSR1LMNAMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |