SCHEMBL11367889

SCHEMBL11367889

Cc1ccc(O)c(C(=O)c2cccc(Cl)c2Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.58
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 2/20 0.58
LMNA P02545 2/20 0.58
CSNK2A1 P68400 1/20 0.50
TSHR P16473 1/20 0.47
CYP2C9 P11712 1/20 0.45
POLB P06746 1/20 0.44
MAPT P10636 3/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 1/20 0.44
PKM P14618 3/20 0.44
CXCL12 P48061 1/20 0.43
HTT P42858 3/20 0.43
GRM5 P41594 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 2/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11372015 0.88 KMT2A (0.58) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL144475 0.87 KMT2A (0.70) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL7831968 0.84 KMT2A (0.57) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL8757108 0.82 TSHR (0.55) TSHRCYP2C9ALDH1A1PKMCXCL12
SCHEMBL11500852 0.81 CSNK2A1 (0.72) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL21550111 0.80 TSHR (0.46) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL5962983 0.80 GSTA1 (0.62) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL7032023 0.79 TSHR (0.71) TSHRCYP2C9POLBALDH1A1PKM
SCHEMBL11756492 0.77 CSNK2A1 (0.56) RAB9AKMT2AKDM4EMEN1LMNA
SCHEMBL1960435 0.76 CSNK2A1 (0.70) RAB9AKMT2AKDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4244970-A WITH A 2-HYDROXYBENZOPHENONE FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) 1981-01-13 US disclosed