Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372015 | 0.87 | KMT2A (0.58) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL11367889 | 0.87 | RAB9A (0.58) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL144223 | 0.87 | KMT2A (0.57) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL5962983 | 0.86 | GSTA1 (0.62) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL9717031 | 0.85 | ABCB1 (0.56) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL7208739 | 0.84 | RAB9A (0.59) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL11500852 | 0.84 | CSNK2A1 (0.72) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL7831968 | 0.83 | KMT2A (0.57) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL9654244 | 0.83 | RECQL (0.71) | KMT2ARAB9AMEN1LMNAKDM4E | |
| SCHEMBL145258 | 0.83 | RECQL (0.70) | KMT2ARAB9AMEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613819-B2 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2020-11-25 | — | — | EP | claimed |
| EP-2613819-B1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2018-01-10 | — | — | EP | claimed |
| CN-103209717-B | Lubricious coatings for medical devices | BIOINTERACTIONS LTD | 2015-04-08 | — | — | CN | claimed |
| US-8541498-B2 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD. (GB) | 2013-09-24 | — | — | US | claimed |
| EP-2613819-A1 | Lubricious coatings for medical devices | Biointeractions Ltd. (GB) | 2013-07-17 | — | — | EP | claimed |
| WO-2012032283-A1 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD (GB) | 2012-03-15 | — | — | WO | claimed |
| US-20120059111-A1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD. (GB) | 2012-03-08 | — | — | US | claimed |
| EP-2613819-B2 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2020-11-25 | — | — | EP | disclosed |
| EP-2613819-B1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD (GB) | 2018-01-10 | — | — | EP | disclosed |
| US-8541498-B2 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD. (GB) | 2013-09-24 | — | — | US | disclosed |
| EP-2613819-A1 | Lubricious coatings for medical devices | Biointeractions Ltd. (GB) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032283-A1 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD (GB) | 2012-03-15 | — | — | WO | disclosed |
| US-20120059111-A1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BIOINTERACTIONS LTD. (GB) | 2012-03-08 | — | — | US | disclosed |
| US-5434264-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
| US-5300642-A | α, α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0311010-B1 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | DU PONT MERCK PHARMA (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0532054-A1 | Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5173489-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0311010-A2 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |