SCHEMBL1960435

SCHEMBL1960435

Cc1ccc(O)c(C(=O)c2ccccc2C(=O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.70
ALDH1A1 P00352 4/20 0.68
AKR1C3 P42330 2/20 0.59
POLB P06746 1/20 0.58
KMT2A Q03164 3/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
MCL1 Q07820 2/20 0.53
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
HMGB1 P09429 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5962983 0.87 GSTA1 (0.62) CSNK2A1ALDH1A1KMT2ACYP3A4CYP2C9
SCHEMBL7820814 0.86 CSNK2A1 (0.53) CSNK2A1ALDH1A1AKR1C3POLBKMT2A
SCHEMBL12325927 0.86 ALDH1A1 (0.68) CSNK2A1ALDH1A1AKR1C3POLBKMT2A
SCHEMBL11500852 0.85 CSNK2A1 (0.72) CSNK2A1ALDH1A1POLBKMT2ACYP2C9
SCHEMBL11756492 0.84 CSNK2A1 (0.56) CSNK2A1ALDH1A1KMT2ACYP3A4CYP2C9
SCHEMBL7648043 0.84 AKR1C3 (0.61) CSNK2A1ALDH1A1AKR1C3POLBKMT2A
SCHEMBL127149 0.83 CSNK2A1 (1.00) CSNK2A1ALDH1A1KMT2ACYP3A4CYP2C9
SCHEMBL29740060 0.83 CSNK2A1 (1.00) CSNK2A1ALDH1A1KMT2ACYP3A4CYP2C9
SCHEMBL11881624 0.83 CSNK2A1 (0.60) CSNK2A1ALDH1A1AKR1C3POLBKMT2A
SCHEMBL29823118 0.82 CSNK2A1 (0.63) CSNK2A1AKR1C3POLBKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3419966-B1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC (CH) 2020-03-25 EP disclosed
US-20110297228-A1 UV BLOCKING FLUOROPOLYMER FILM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2011-12-08 US disclosed
WO-2011071847-A2 UV BLOCKING FLUOROPOLYMER FILM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2011-06-16 WO disclosed
US-20100184887-A1 HYBRID NANOPARTICLES BASF SE (DE) 2010-07-22 US disclosed
US-20100184887-A1 HYBRID NANOPARTICLES BASF SE (DE) 2010-07-22 US disclosed
WO-2009080427-A1 METHOD FOR PRODUCING UV-ABSORBING HYBRID MATERIALS BASF SE (DE) 2009-07-02 WO disclosed
WO-2009003981-A2 HYBRID NANOPARTICLES BASF SE (DE) 2009-01-08 WO disclosed
WO-2007044184-A1 WATER SOLUBLE PHOTOINITIATOR ALBEMARLE CORPORATION (US) 2007-04-19 WO disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-4954631-A INFRARED ABSORPTION; BLACK SHIN NISSO KAKO CO., LTD. (JP) 1990-09-04 US disclosed
US-4826806-A CHROMOGENIC DYES SHIN NISSO KAKO CO., LTD. (JP) 1989-05-02 US disclosed
US-4058529-A Polycyclic amino derivatives of pyrrolidone and piperidone CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184887-A1 HYBRID NANOPARTICLES RAB5IF, TTPA, PRNP CSNK2A1 1995/4885ALDH1A1 182/4885AKR1C3 1768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.