Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908075 | 0.80 | ALOX5 (0.66) | ALOX5PTGS1PTGS2ABL1MAPT | |
| SCHEMBL11558232 | 0.78 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ABL1 | |
| SCHEMBL907934 | 0.76 | ABL1 (0.64) | ALOX5PTGS1PTGS2ABL1MAPT | |
| SCHEMBL7719095 | 0.76 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ABL1MAPT | |
| SCHEMBL7721910 | 0.76 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ABL1MAPT | |
| SCHEMBL10739294 | 0.76 | MAOB (0.52) | ALOX5PTGS1PTGS2ABL1KDM4E | |
| Bw-755C SCHEMBL2573191 | 0.76 | ALOX5 (1.00) | ALOX5PTGS1PTGS2ABL1MAPT | |
| Bw-755C SCHEMBL1040411 | 0.75 | ALOX5 (0.97) | ALOX5PTGS1PTGS2ABL1MAPT | |
| SCHEMBL7719905 | 0.75 | ALOX5 (0.58) | ALOX5PTGS1PTGS2ABL1MAPT | |
| SCHEMBL7719890 | 0.74 | ALOX5 (0.58) | ALOX5PTGS1PTGS2ABL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268436-A | OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |