Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PLA2G10 | O15496 | 15/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | PTEN | P60484 | 1/20 | 0.42 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368286 | 0.78 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ABL1 | |
| SCHEMBL2554494 | 0.74 | ALDH1A1 (0.55) | PLA2G10PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL29951752 | 0.72 | ALDH1A1 (0.54) | PLA2G10PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL15330250 | 0.72 | ALDH1A1 (0.54) | PLA2G10PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL11558230 | 0.72 | PTGS1 (0.50) | ALOX5PTGS1PTGS2ABL1 | |
| SCHEMBL11562454 | 0.71 | PLA2G10 (0.47) | PLA2G10PLA2G2APLA2G5PTPRBCDC25A | |
| SCHEMBL7275526 | 0.71 | PLA2G10 (0.45) | PLA2G10PLA2G2APTPRBCDC25ACDC25B | |
| SCHEMBL30151165 | 0.70 | KMO (0.58) | PLA2G10KEAP1 | |
| SCHEMBL7719095 | 0.70 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ABL1 | |
| Sulfuric Acid SCHEMBL11106611 | 0.70 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4149005-A | Process for preparing 1-phenyl-3-aminopyrazoles | MONTEDISON S.P.A. (IT) | 1979-04-10 | — | — | US | disclosed |