SCHEMBL11368397

SCHEMBL11368397

CCCCCc1ccc(-c2cc(O)ccc2O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.61
PTGS2 P35354 3/20 0.61
ESR1 P03372 2/20 0.61
ADRA2A P08913 2/20 0.61
ADORA3 P0DMS8 2/20 0.61
TACR2 P21452 2/20 0.61
SLC6A2 P23975 2/20 0.61
SLC6A4 P31645 2/20 0.61
SLC6A3 Q01959 2/20 0.61
TP53 P04637 2/20 0.61
KDM4E B2RXH2 1/20 0.61
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.61
SHBG P04278 1/20 0.61
HSPD1 P10809 1/20 0.61
ADRB3 P13945 1/20 0.61
HTR2C P28335 1/20 0.61
HSPE1 P61604 1/20 0.61
HIF1A Q16665 1/20 0.61
TST Q16762 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31741252 0.89 PTGS2 (0.62) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL7078235 0.88 PTGS2 (0.60) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL9818748 0.85 ALOX5 (0.58) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL28653265 0.85 CNR1 (0.61) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL28141951 0.81 CA2 (0.59) ESR1KDM4EALDH1A1ALOX15ALOX5
SCHEMBL7253630 0.81 PTGS2 (0.84) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL982418 0.81 PTGS2 (0.84) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL29733599 0.80 ESR1 (0.56) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL21321639 0.80 RARB (0.64) CYP3A4PTGS2ESR1ADRA2AADORA3
SCHEMBL10527286 0.80 ALDH1A1 (0.55) CYP3A4PTGS2ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed
US-4082553-A INTERIMAGE EFFECTS WITH SPONTANEOUSLY DEVELOPABLE SILVER HALIDE EASTMAN KODAK COMPANY (US) 1978-04-04 US disclosed