Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367120 | 0.96 | ALDH1A1 (0.59) | ALDH1A1SLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL11371084 | 0.95 | ALDH1A1 (0.57) | ALDH1A1SLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL11369651 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL9624259 | 0.84 | TP53 (0.49) | ALDH1A1SLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL31576799 | 0.84 | TP53 (0.49) | ALDH1A1SLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL11366159 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SLC6A2SLC6A4LMNAMAPT | |
| SCHEMBL11359810 | 0.79 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2L3MBTL1TP53MEN1 | |
| SCHEMBL11363386 | 0.76 | ADRB1 (0.43) | ALDH1A1SLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL11364283 | 0.76 | ALDH1A1 (0.67) | ALDH1A1ADRB1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL11358737 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |