SCHEMBL31576799

SCHEMBL31576799

O=c1n(-c2ccc(Cl)c(Cl)c2)c(=O)n(-c2ccc(Cl)c(Cl)c2)c(=O)n1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.49
NOTUM Q6P988 3/20 0.47
SLC6A2 P23975 4/20 0.46
SLC6A4 P31645 4/20 0.46
SLC6A3 Q01959 3/20 0.46
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
GFER P55789 1/20 0.45
MAPT P10636 3/20 0.44
KMT2A Q03164 2/20 0.44
BCL2A1 Q16548 1/20 0.44
ADAM17 P78536 1/20 0.44
MEN1 O00255 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
ADRB1 P08588 1/20 0.44
RAD51 Q06609 1/20 0.43
RGS4 P49798 1/20 0.42
RGS8 P57771 1/20 0.42
LMNA P02545 1/20 0.42
ALOX12 P18054 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9624259 1.00 TP53 (0.49) TP53NOTUMSLC6A2SLC6A4SLC6A3
SCHEMBL11368471 0.84 ALDH1A1 (0.64) TP53SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL11367120 0.84 ALDH1A1 (0.59) TP53NOTUMSLC6A2SLC6A4SLC6A3
SCHEMBL11371084 0.82 ALDH1A1 (0.57) SLC6A2SLC6A4SLC6A3ALDH1A1HTT
SCHEMBL11608487 0.80 TP53 (0.53) TP53NOTUMSLC6A2SLC6A4SLC6A3
SCHEMBL9624054 0.80 L3MBTL1 (0.55) ALDH1A1GFERMAPTKMT2AMEN1
SCHEMBL11606006 0.80 TP53 (0.39) TP53NOTUMSLC6A2SLC6A4ALDH1A1
SCHEMBL11612319 0.77 RAD51 (0.42) TP53NOTUMALDH1A1HTTGFER
SCHEMBL11610374 0.77 TP53 (0.38) TP53NOTUMALDH1A1HTTGFER
SCHEMBL11308506 0.77 POLB (0.67) TP53NOTUMALDH1A1HTTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103919-A1 PROCESS FOR PRODUCING SUBSTITUTED PHENYL UREA DERIVATIVES LANXESS DEUTSCHLAND GMBH (DE) 2025-05-22 WO disclosed
EP-4556462-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLUREA DERIVATIVES LANXESS Deutschland GmbH (DE) 2025-05-21 EP disclosed