Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117726 | 0.79 | HTR2C (0.36) | MEN1KMT2ADAOHTR2CCA1 | |
| SCHEMBL116596 | 0.79 | MEN1 (0.39) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL24112230 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL24112725 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL5873718 | 0.69 | EGFR (0.47) | ALDH1A1MEN1KMT2AHTR5A | |
| SCHEMBL20991196 | 0.69 | MEN1 (0.47) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL9791473 | 0.64 | MEN1 (0.55) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL8519908 | 0.63 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL31607527 | 0.63 | MEN1 (0.58) | ALDH1A1MEN1KMT2ACREBBPHTR2C | |
| SCHEMBL10717778 | 0.62 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252723-A | Air oxidation of oxindoles to isatins | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1981-02-24 | — | — | US | disclosed |
| US-4188325-A | Isatin process and products | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 1980-02-12 | — | — | US | disclosed |
| US-4186132-A | Isatin products | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1980-01-29 | — | — | US | disclosed |