Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368666 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AHTR5ACA12CA1 | |
| SCHEMBL24112851 | 0.78 | MEN1 (0.42) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL117726 | 0.78 | HTR2C (0.36) | MEN1KMT2AGAAMAPTCACNA1B | |
| SCHEMBL24112722 | 0.78 | MEN1 (0.42) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL6639940 | 0.73 | NOS3 (0.44) | CHRNB2CHRNA4GAAMAPTGFER | |
| SCHEMBL2872999 | 0.70 | ALDH1A1 (0.38) | GAAALDH1A1NPSR1TDP1PTPN7 | |
| SCHEMBL5873718 | 0.68 | EGFR (0.47) | MEN1KMT2AHTR5AALDH1A1 | |
| SCHEMBL18553863 | 0.67 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13061796 | 0.64 | KDM1A (0.40) | MEN1KMT2ACHRNB2CHRNA4MAPT | |
| SCHEMBL18553860 | 0.64 | MEN1 (0.40) | MEN1KMT2AGAAMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242934-B2 | Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses | BAYER CROPSCIENCE AG (DE) | 2016-01-26 | — | — | US | disclosed |
| EP-2424835-B1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES | BAYER IP GMBH (DE) | 2015-07-01 | — | — | EP | disclosed |
| CN-102459163-B | Process for the preparation of oxindoles and ortho-substituted anilines and their use as synthesis intermediates | BAYER CROPSCIENCE AG | 2015-05-13 | — | — | CN | disclosed |
| US-20130281711-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8492590-B2 | Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses | BAYER CROPSCIENCE AG (DE) | 2013-07-23 | — | — | US | disclosed |
| WO-2012028162-A1 | PROCESS FOR PREPARING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2424835-A1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES | Bayer CropScience AG (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010127786-A1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| EP-2246326-A1 | Method for producing oxindoles and ortho-substituted anilines and their use as intermediate products for syntheses | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281711-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | TH, OXSR1, AOX1 | MEN1 3478/4885KMT2A 1699/4885CHRNB2 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.