Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112230 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL24112725 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL11368666 | 0.63 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL24029075 | 0.63 | TP53 (0.40) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL2987129 | 0.63 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL24019657 | 0.63 | TP53 (0.40) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL11368672 | 0.63 | DAO (0.40) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL4474244 | 0.61 | HTR2C (0.49) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL13627318 | 0.61 | HTR2C (0.49) | ALDH1A1MEN1KMT2ACREBBPDAO | |
| SCHEMBL4476708 | 0.61 | HTR2C (0.49) | ALDH1A1MEN1KMT2ACREBBPDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934282-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015535-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |