Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 6/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | HTR1D | P28221 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368666 | 0.79 | ALDH1A1 (0.43) | HTR2CDAOHTR5ACA12CA1 | |
| SCHEMBL24112226 | 0.78 | PGR (0.49) | HTR2CNSD2BCHEDAOCES1 | |
| SCHEMBL24112933 | 0.78 | PGR (0.49) | HTR2CNSD2BCHEDAOCES1 | |
| SCHEMBL5873718 | 0.68 | EGFR (0.47) | HTR5AMEN1KMT2AALOX12 | |
| SCHEMBL17257671 | 0.65 | HTR2C (0.38) | HTR2CNSD2BCHEDAOCES1 | |
| SCHEMBL11095090 | 0.65 | SLC6A2 (0.39) | HTR2CNSD2BCHEDAOCES1 | |
| SCHEMBL24029077 | 0.63 | CACNB4 (0.40) | NSD2BCHEDAOCES1AHR | |
| SCHEMBL117727 | 0.63 | CACNB4 (0.40) | NSD2BCHEDAOCES1AHR | |
| SCHEMBL23835719 | 0.63 | PGR (0.52) | NSD2BCHEDAOCES1GAA | |
| SCHEMBL10840849 | 0.63 | ALDH1A1 (0.45) | HTR2CGAAPGRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242934-B2 | Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses | BAYER CROPSCIENCE AG (DE) | 2016-01-26 | — | — | US | disclosed |
| EP-2424835-B1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES | BAYER IP GMBH (DE) | 2015-07-01 | — | — | EP | disclosed |
| CN-102459163-B | Process for the preparation of oxindoles and ortho-substituted anilines and their use as synthesis intermediates | BAYER CROPSCIENCE AG | 2015-05-13 | — | — | CN | disclosed |
| US-20130281711-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8492590-B2 | Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses | BAYER CROPSCIENCE AG (DE) | 2013-07-23 | — | — | US | disclosed |
| WO-2012028162-A1 | PROCESS FOR PREPARING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2424835-A1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES | Bayer CropScience AG (DE) | 2012-03-07 | — | — | EP | disclosed |
| US-20110118478-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2010127786-A1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| EP-2246326-A1 | Method for producing oxindoles and ortho-substituted anilines and their use as intermediate products for syntheses | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118478-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | TH, OXSR1, AOX1 | HTR2C 124/4885NSD2 1498/4885BCHE 619/4885 |
| US-20130281711-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | TH, OXSR1, AOX1 | HTR2C 124/4885NSD2 1498/4885BCHE 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.