Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788872 | 0.83 | KIF11 (0.43) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL28788871 | 0.83 | KIF11 (0.43) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL9542642 | 0.80 | RAB9A (0.39) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14328250 | 0.80 | RAB9A (0.39) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29442058 | 0.74 | KDM4E (0.41) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9218476 | 0.74 | KDM4E (0.41) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18114343 | 0.73 | MIF (0.41) | MEN1KMT2AMAOAMAOBRAB9A | |
| SCHEMBL22534057 | 0.73 | MIF (0.41) | MEN1KMT2AMAOAMAOBRAB9A | |
| Hydrochloric Acid SCHEMBL22534094 | 0.72 | MIF (0.40) | MEN1KMT2AMAOAMAOBRAB9A | |
| Hydrochloric Acid SCHEMBL22534093 | 0.72 | MIF (0.40) | MEN1KMT2AMAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264620-A | HYPOTENSIVE AGENTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |