Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788871 | 1.00 | KIF11 (0.43) | KIF11CA1CA2NOTUMRAB9A | |
| SCHEMBL11368798 | 0.83 | HTR2B (0.42) | RAB9AKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL29788018 | 0.82 | CA1 (0.41) | KIF11CA1CA2ALDH1A1CASP3 | |
| SCHEMBL2038955 | 0.82 | CA1 (0.41) | KIF11CA1CA2ALDH1A1CASP3 | |
| SCHEMBL29788207 | 0.82 | CA1 (0.41) | KIF11CA1CA2ALDH1A1CASP3 | |
| SCHEMBL2038953 | 0.82 | CA1 (0.41) | KIF11CA1CA2ALDH1A1CASP3 | |
| SCHEMBL9542642 | 0.78 | RAB9A (0.39) | CA1CA2RAB9AKMT2AMAPT | |
| SCHEMBL14328250 | 0.78 | RAB9A (0.39) | CA1CA2RAB9AKMT2AMAPT | |
| SCHEMBL14457930 | 0.74 | NOS1 (0.42) | KIF11CA1CA2RAB9ACYP2A6 | |
| SCHEMBL4505854 | 0.74 | L3MBTL1 (0.43) | CA1CA2NOTUMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |