Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136902 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL1137010 | 0.84 | HSPB1 (0.41) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL2257136 | 0.82 | MMP13 (0.41) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL2257142 | 0.82 | MMP13 (0.41) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL1137142 | 0.82 | SLC22A12 (0.41) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL28770683 | 0.81 | MET (0.36) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL12363119 | 0.81 | NAMPT (0.41) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL14045145 | 0.80 | HSPB1 (0.50) | ALDH1A1MAPTMAPK1L3MBTL1MET | |
| SCHEMBL1137649 | 0.79 | CYP11B1 (0.41) | ALDH1A1MAPTMETCYP19A1CYP11B1 | |
| SCHEMBL1137363 | 0.79 | POLB (0.42) | ALDH1A1MAPTMAPK1L3MBTL1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737451-B1 | MONOCYCLIC HETEROCYCLES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-23 | — | — | EP | disclosed |