Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 6/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543696 | 0.90 | CYP2J2 (0.63) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL11828383 | 0.89 | CYP2J2 (0.62) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL11833697 | 0.89 | CYP2J2 (0.62) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL11544185 | 0.89 | CYP2J2 (0.62) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| SCHEMBL11371371 | 0.88 | OPRK1 (0.53) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| SCHEMBL11831920 | 0.86 | CYP2J2 (0.59) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| SCHEMBL11545924 | 0.86 | DRD2 (0.64) | OPRK1OPRM1OPRD1DRD2HTR1A | |
| SCHEMBL11379114 | 0.86 | OPRD1 (0.47) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| SCHEMBL11864675 | 0.86 | CYP2J2 (0.58) | CYP2J2OPRK1OPRM1OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL11831531 | 0.85 | CYP2J2 (0.58) | CYP2J2OPRK1OPRM1OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | claimed |
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |