SCHEMBL11370784

SCHEMBL11370784

N#Cc1cncc(N)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293682 0.82 CYP11B1 (0.44)
SCHEMBL19555999 0.76
Ammonia Solution, Strong SCHEMBL28120837 0.74 CYP11B1 (0.38)
SCHEMBL1604498 0.73
SCHEMBL945452 0.71
SCHEMBL2632677 0.71
SCHEMBL21664084 0.71
SCHEMBL6375657 0.71
SCHEMBL21044544 0.70 CYP11B2 (0.52)
SCHEMBL21044154 0.70 CYP11B2 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090270-A1 ORGANIC ELECTRONIC ELEMENT AND COMPOUND TOSOH CORPORATION (JP) 2026-03-26 US disclosed
EP-4626191-A1 ORGANIC ELECTRONIC ELEMENT AND COMPOUND Tosoh Corporation (JP) 2025-10-01 EP disclosed
CN-120167151-A Organic electronic component and compound 东曹株式会社 2025-06-17 CN disclosed
EP-3848370-B1 TYK2 INHIBITORS AND USES THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2025-05-07 EP disclosed
WO-2024111206-A1 ORGANIC ELECTRONIC ELEMENT AND COMPOUND 東ソー株式会社 2024-05-30 WO disclosed
US-RE49934-E1 Inhibitors of cellular metabolic processes SERVIER PHARMACEUTICALS LLC (US) 2024-04-23 US disclosed
WO-2023028338-A2 MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2023-03-02 WO disclosed
CN-115448916-A TYK2 inhibitor and application thereof 林伯士拉克许米公司 2022-12-09 CN disclosed
CN-109952303-B TYK2 inhibitor and application thereof 林伯士拉克许米公司 2022-10-21 CN disclosed
CN-109890822-B Inhibitors of cellular metabolic processes 安吉奥斯医药品有限公司 2022-08-30 CN disclosed
WO-2018039972-A1 INHIBITORS OF CELLULAR METABOLIC PROCESSES AGIOS PHARMACEUTICALS, INC. (US) 2018-03-08 WO disclosed
WO-2018022865-A1 COELENTERAZINE ANALOGUES PROMEGA CORPORATION (US) 2018-02-01 WO disclosed
US-20180030059-A1 COELENTERAZINE ANALOGUES JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-02-01 US disclosed
EP-2240451-B1 Isoquinolinone derivatives substituted with a purine useful as PI3K inhibitors INTELLIKINE LLC (US) 2017-08-09 EP disclosed
EP-3150609-A1 PROCESS FOR PREPARING CERTAIN CHEMICAL ENTITIES Intellikine, LLC (US) 2017-04-05 EP disclosed
EP-2951170-A2 FLAP MODULATORS Janssen Pharmaceutica, N.V. (BE) 2015-12-09 EP disclosed
WO-2014121055-A2 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-07 WO disclosed
US-4293552-A Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas ELI LILLY AND COMPANY (US) 1981-10-06 US disclosed
US-4160834-A INSECTICIDES ELI LILLY AND COMPANY (US) 1979-07-10 US disclosed
US-4083977-A Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas ELI LILLY AND COMPANY (US) 1978-04-11 US disclosed