Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044154 | 0.81 | CYP11B2 (0.56) | CYP11B2CYP11B1IRAK4MEN1NPC1 | |
| SCHEMBL21044087 | 0.75 | PIK3CD (0.56) | CYP11B2CYP11B1PIK3CDMKNK1MKNK2 | |
| SCHEMBL23121297 | 0.75 | MKNK1 (0.46) | PIK3CDMKNK1MKNK2MEN1NPC1 | |
| SCHEMBL13097164 | 0.75 | CYP11B1 (0.44) | CYP11B2CYP11B1PIK3CDMKNK1MKNK2 | |
| SCHEMBL8070286 | 0.74 | CYP11B2 (0.55) | CYP11B2CYP11B1IRAK4MEN1RAB9A | |
| SCHEMBL21044075 | 0.74 | CYP11B2 (0.56) | CYP11B2CYP11B1IRAK4NPC1RAB9A | |
| SCHEMBL21044056 | 0.74 | CYP11B2 (0.63) | CYP11B2CYP11B1IRAK4MAPT | |
| SCHEMBL22869136 | 0.74 | CYP11B2 (0.72) | CYP11B2CYP11B1IRAK4 | |
| SCHEMBL30338462 | 0.73 | CYP11B2 (0.51) | CYP11B2CYP11B1MKNK1MKNK2KDM4E | |
| SCHEMBL28145764 | 0.73 | CYP11B1 (0.55) | CYP11B2CYP11B1MKNK1MKNK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717459-B1 | COMPOUNDS | STEP PHARMA S A S (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2023-05-23 | — | — | US | disclosed |
| US-20210002269-A1 | COMPOUNDS | STEP PHARMA S.A.S. (FR) | 2021-01-07 | — | — | US | disclosed |
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | CYP11B2 1869/4885CYP11B1 1418/4885PIK3CD 2075/4885 |
| US-20210002269-A1 | COMPOUNDS | UGT1A1, CYP1A1, CYP19A1 | CYP11B2 6/4885CYP11B1 5/4885PIK3CD 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.