Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374984 | 0.87 | ESR2 (0.47) | CNR1CNR2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11370725 | 0.85 | PDE4B (0.47) | HCAR1CNR1CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11368889 | 0.84 | ALDH1A1 (0.52) | CNR1CNR2SLC5A1SLC5A2MAPT | |
| SCHEMBL11372681 | 0.83 | POLB (0.48) | HCAR1CNR1CNR2SLC5A1SLC5A2 | |
| SCHEMBL11372451 | 0.83 | ESR2 (0.52) | CNR1CNR2GABRA2ESR1ESR2 | |
| SCHEMBL11074341 | 0.81 | CNR1 (0.54) | CNR1CNR2MEN1KMT2ASLC5A1 | |
| SCHEMBL11082376 | 0.73 | SLC5A1 (0.55) | HCAR1SLC5A1SLC5A2MAPTNPC1 | |
| SCHEMBL11380037 | 0.72 | KDM4E (0.41) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11374217 | 0.72 | CNR1 (0.53) | CNR1CNR2KMT2AMAPTMAPK1 | |
| SCHEMBL11306858 | 0.71 | PDE4B (0.50) | KMT2AALDH1A1GAAGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | claimed |