Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074341 | 0.90 | CNR1 (0.54) | ALDH1A1CNR1CNR2MAPTLMNA | |
| SCHEMBL11374217 | 0.87 | CNR1 (0.53) | ALDH1A1CNR1CNR2MAPTLMNA | |
| SCHEMBL11369431 | 0.84 | CNR1 (0.51) | ALDH1A1CNR1CNR2POLBMAPT | |
| SCHEMBL10979002 | 0.84 | CNR1 (0.51) | ALDH1A1CNR1CNR2POLBLMNA | |
| SCHEMBL11372160 | 0.84 | HCAR1 (0.43) | ALDH1A1CNR1CNR2MAPTSLC5A1 | |
| SCHEMBL10977927 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CNR1CNR2MAPTLMNA | |
| SCHEMBL844904 | 0.80 | CNR1 (0.72) | ALDH1A1CNR1CNR2POLBMAPT | |
| SCHEMBL11081687 | 0.77 | CNR1 (0.59) | ALDH1A1CNR1CNR2MAPTLMNA | |
| SCHEMBL11068971 | 0.76 | CNR1 (0.58) | ALDH1A1CNR1CNR2MAPTLMNA | |
| SCHEMBL11071848 | 0.75 | CNR1 (0.57) | ALDH1A1CNR1CNR2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | claimed |
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | disclosed |