Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368889 | 0.90 | ALDH1A1 (0.52) | CNR1CNR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11081687 | 0.88 | CNR1 (0.59) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL11071848 | 0.86 | CNR1 (0.57) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL10973972 | 0.85 | CNR1 (0.57) | CNR1CNR2ALDH1A1GAALMNA | |
| SCHEMBL11070514 | 0.85 | CNR1 (0.57) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL11074709 | 0.84 | CNR1 (0.56) | CNR1CNR2ALDH1A1GAAADORA1 | |
| SCHEMBL11079598 | 0.84 | CNR1 (0.56) | CNR1CNR2ALDH1A1LMNAADORA1 | |
| SCHEMBL10972776 | 0.83 | CNR1 (0.54) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL11372160 | 0.81 | HCAR1 (0.43) | CNR1CNR2ALDH1A1MAPTGAA | |
| SCHEMBL11340568 | 0.81 | CNR1 (0.52) | CNR1CNR2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | disclosed |