Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 4/20 | 0.48 |
| ▸ | ACACA | Q13085 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557533 | 0.94 | TP53 (0.55) | L3MBTL1SMN1; SMN2MAPK1TSHRTP53 | |
| SCHEMBL10766584 | 0.88 | LTA4H (0.55) | SMN1; SMN2LMNAMAPK1TSHRTP53 | |
| SCHEMBL30887385 | 0.87 | PARP10 (0.56) | L3MBTL1PLK1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL2299624 | 0.87 | PARP10 (0.56) | L3MBTL1PLK1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL10996690 | 0.85 | L3MBTL1 (0.60) | L3MBTL1PLK1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8323514 | 0.83 | L3MBTL1 (0.53) | L3MBTL1PLK1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL3685459 | 0.83 | L3MBTL1 (0.53) | L3MBTL1PLK1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL10995367 | 0.83 | L3MBTL1 (0.58) | L3MBTL1PLK1SMN1; SMN2LMNAMAPT | |
| SCHEMBL12114015 | 0.83 | L3MBTL1 (0.54) | L3MBTL1LMNAMAPTMAPK1TSHR | |
| SCHEMBL11680771 | 0.81 | L3MBTL1 (0.60) | L3MBTL1PLK1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263311-A | ANTIARTHRITIC AGENTS | SMITHKLINE CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |