SCHEMBL3685459

SCHEMBL3685459

CCCOc1ccc(C(O)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.53
LMNA P02545 2/20 0.53
ACACB O00763 6/20 0.50
ACACA Q13085 3/20 0.50
CYP2C19 P33261 1/20 0.50
PLK1 P53350 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 2/20 0.49
GPR88 Q9GZN0 1/20 0.49
POLB P06746 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323514 1.00 L3MBTL1 (0.53) L3MBTL1LMNAACACBACACACYP2C19
SCHEMBL3685401 0.93 LMNA (0.57) L3MBTL1LMNASMN1; SMN2POLBTDP1
SCHEMBL31558760 0.90 LMNA (0.62) L3MBTL1LMNAPOLBTDP1
SCHEMBL9191267 0.89 LMNA (0.64) LMNAPOLB
SCHEMBL9189425 0.89 LMNA (0.64) LMNAPOLB
SCHEMBL9194774 0.89 LMNA (0.64) LMNAPOLB
SCHEMBL9193732 0.89 LMNA (0.64) LMNAPOLB
SCHEMBL30967691 0.86 ESR1 (0.50) L3MBTL1LMNAACACBACACACYP2C19
SCHEMBL9380908 0.86 RARB (0.59) LMNASMN1; SMN2POLB
SCHEMBL9380903 0.86 RARB (0.59) LMNASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005420-A Disperse dye for superfine denier fiber and synthesis method thereof 青岛大学 2025-05-16 CN disclosed
CN-108047033-B Reaction device and method for preparing mandelic acid compound 江西科苑生物药业有限公司 2023-12-01 CN disclosed
US-7737286-B2 α-Hydroxy-benzeneacetic acid derivatives, and compounds having two 5-membered latone rings fused to central cyclohexa-1,4-diene nucleus based upon the same, and uses of the compounds KYUNG-IN SYNTHETIC CORPORATION (KR) 2010-06-15 US disclosed
EP-1663934-A4 ALPHA-HYDROXY-BENZENEACETIC ACID DERIVATIVES, AND COMPOUNDS HAVING TWO 5-MEMBERED LACTONE RINGS FUSED TO CENTRAL CYCLOHEXA-1,4-DIENE NUCLEUS BASED UPON THE SAME, AND USES OF THE COMPOUNDS KYUNG IN SYNTHETIC CORP (KR) 2008-10-01 EP disclosed
US-20070220688-A1 Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds KYUNG-IN SYNTHETIC CORPORATION (KR) 2007-09-27 US disclosed
EP-1663934-A1 ALPHA-HYDROXY-BENZENEACETIC ACID DERIVATIVES, AND COMPOUNDS HAVING TWO 5-MEMBERED LACTONE RINGS FUSED TO CENTRAL CYCLOHEXA-1,4-DIENE NUCLEUS BASED UPON THE SAME, AND USES OF THE COMPOUNDS KYUNG-IN SYNTHETIC CORPORATION (KR) 2006-06-07 EP disclosed
WO-2005028409-A1 ALPHA-HYDROXY-BENZENEACETIC ACID DERIVATIVES, AND COMPOUNDS HAVING TWO 5-MEMBERED LACTONE RINGS FUSED TO CENTRAL CYCLOHEXA-1,4-DIENE NUCLEUS BASED UPON THE SAME, AND USES OF THE COMPOUNDS KYUNG-IN SYNTHETIC CORPORATION (KR) 2005-03-31 WO disclosed
EP-0559345-B1 Polycyclic dyes BASF AG (DE) 1999-05-06 EP disclosed
EP-0560499-B1 Process for the preparation of polycyclic dyes BASF AG (DE) 1997-07-09 EP disclosed
EP-0252406-B2 Process for the manufacture of polycyclic compounds BAYER AG (DE) 1996-03-20 EP disclosed
US-5281241-A Benzo(1,2-b:4,5-b')difuran derivatives ZENECA LIMITED (GB) 1994-01-25 US disclosed
EP-0574148-A1 Polycyclic dyes ZENECA LIMITED (GB) 1993-12-15 EP disclosed
EP-0560499-A1 Polycyclic dyes ZENECA LIMITED (GB) 1993-09-15 EP disclosed
EP-0559345-A1 Polycyclic dyes ZENECA LIMITED (GB) 1993-09-08 EP disclosed
EP-0551725-A1 Polycyclic dyes ZENECA LIMITED (GB) 1993-07-21 EP disclosed
US-5220040-A Furan and monoazo dyes having similar wavelength maxima; efficient package dyeing of wound polyester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-06-15 US disclosed
EP-0492893-A2 Mixtures and mixed crystals of dyes ZENECA LIMITED (GB) 1992-07-01 EP disclosed
EP-0252406-A2 Process for the manufacture of polycyclic compounds BAYER AG (DE) 1988-01-13 EP disclosed
EP-0033583-B1 DYESTUFFS COMPRISING TWO 5-MEMBERED HETEROCYCLIC NUCLEI FUSED TO A CENTRAL CYCLOHEXADIENE NUCLEUS, PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR COLOURING SYNTHETIC TEXTILE MATERIALS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-10-12 EP disclosed
EP-0033583-A1 Dyestuffs comprising two 5-membered heterocyclic nuclei fused to a central cyclohexadiene nucleus, processes for their preparation and their use for colouring synthetic textile materials IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070220688-A1 Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds LDHA, HCAR1, HPD L3MBTL1 3566/4885LMNA 79/4885ACACB 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.