Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367938 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1ABCB11USP2LMNA | |
| SCHEMBL11374604 | 0.78 | CXCL8 (0.51) | KMT2AMEN1ABCB11LMNATTR | |
| SCHEMBL11373706 | 0.77 | CXCL8 (0.43) | KMT2AMEN1USP2LMNATTR | |
| SCHEMBL11366409 | 0.76 | TTR (0.50) | KMT2AMEN1ABCB11USP2LMNA | |
| SCHEMBL11380072 | 0.73 | PTGS2 (0.52) | KMT2AMEN1ABCB11USP2LMNA | |
| SCHEMBL11380719 | 0.73 | PHGDH (0.30) | — | |
| SCHEMBL11387892 | 0.72 | CXCL8 (0.48) | KMT2AABCB11USP2LMNATTR | |
| SCHEMBL11370538 | 0.72 | PTGS2 (0.48) | KMT2AMEN1ABCB11USP2LMNA | |
| SCHEMBL11386345 | 0.70 | MEN1 (0.38) | KMT2AMEN1ABCB11LMNACYP2C9 | |
| SCHEMBL11368848 | 0.69 | ALDH1A1 (0.42) | KMT2AUSP2LMNATTRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |