Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379997 | 0.84 | TTR (0.44) | ALDH1A1NPC1RAB9ANQO1KCNH2 | |
| SCHEMBL11356803 | 0.84 | TBK1 (0.44) | KDM4ENPC1RAB9APKMCSNK2A2 | |
| SCHEMBL11375424 | 0.84 | CSNK1D (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11362867 | 0.84 | POLB (0.36) | TP53ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11360752 | 0.82 | MAOA (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11367261 | 0.77 | NT5E (0.45) | NT5EALPGMAPTTP53RXFP1 | |
| SCHEMBL5256371 | 0.73 | ALDH1A1 (0.44) | MAPTRXFP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1611070 | 0.73 | ALPG (0.59) | ALPGMAPTTP53KDM4EALDH1A1 | |
| SCHEMBL16906004 | 0.72 | ALDH1A1 (0.48) | NT5EALPGMAPTTP53KDM4E | |
| SCHEMBL18347522 | 0.71 | IDO1 (0.48) | NT5EMAPTTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | claimed |