Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375182 | 0.84 | NT5E (0.42) | KMT2AALDH1A1CSNK2A1NQO1MEN1 | |
| SCHEMBL11360752 | 0.82 | MAOA (0.47) | TTRKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL11356803 | 0.81 | TBK1 (0.44) | TTRKMT2AGPR35CSNK2A1MEN1 | |
| SCHEMBL11375424 | 0.81 | CSNK1D (0.40) | ALDH1A1GSK3BNPC1RAB9A | |
| SCHEMBL11362867 | 0.81 | POLB (0.36) | KMT2AALDH1A1LMNACSNK2A1CSF1R | |
| SCHEMBL11375422 | 0.77 | GPR35 (0.46) | TTRKMT2AALDH1A1LMNAGPR35 | |
| SCHEMBL11546372 | 0.76 | TTR (0.64) | TTRKMT2AALDH1A1LMNAGPR55 | |
| SCHEMBL5256371 | 0.73 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAMEN1NPC1 | |
| SCHEMBL4092241 | 0.73 | TTR (0.71) | TTRKMT2AALDH1A1CA1CA2 | |
| SCHEMBL11372089 | 0.71 | MKNK2 (0.40) | TTRKMT2AALDH1A1LMNAGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | claimed |