Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12165522 | 0.85 | ATM (0.77) | ATMSMN1; SMN2HTTGAAIDO1 | |
| SCHEMBL12165458 | 0.85 | ATM (0.51) | ATMSMN1; SMN2HTTGAAIDO1 | |
| SCHEMBL7316248 | 0.79 | THRB (0.47) | ATMHTTALDH1A1LMNANPSR1 | |
| SCHEMBL24281081 | 0.75 | SMN1; SMN2 (0.62) | ATMSMN1; SMN2HTTGAAIDO1 | |
| SCHEMBL11490783 | 0.73 | KCNQ2 (0.53) | ATMSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL23573056 | 0.71 | KMT2A (0.45) | ATMGAAIDO1TDO2LMNA | |
| SCHEMBL21887878 | 0.68 | KMT2A (0.48) | SMN1; SMN2HTTGAALMNAMAPT | |
| SCHEMBL16865428 | 0.68 | MMP9 (0.56) | ATMSMN1; SMN2CYP3A4 | |
| SCHEMBL14612689 | 0.67 | PDK2 (0.50) | ATMSMN1; SMN2HTTGAAIDO1 | |
| SCHEMBL7834463 | 0.67 | PGR (0.59) | ATMSMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244954-A | Acridine compounds and methods of combatting viruses with them | STERLING DRUG INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |