Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12165443 | 0.85 | KMT2A (0.44) | KMT2AMEN1LMNAP2RX1P2RX3 | |
| SCHEMBL12165439 | 0.85 | KMT2A (0.44) | KMT2AMEN1LMNAP2RX1P2RX3 | |
| SCHEMBL27889418 | 0.84 | POLB (0.43) | KMT2AMEN1LMNAP2RX1P2RX3 | |
| SCHEMBL18025761 | 0.84 | KMT2A (0.66) | KMT2AMEN1LMNAPOLBCASP6 | |
| SCHEMBL209276 | 0.84 | KMT2A (0.66) | KMT2AMEN1LMNAPOLBCASP6 | |
| SCHEMBL18552443 | 0.84 | KMT2A (0.66) | KMT2AMEN1LMNAPOLBCASP6 | |
| SCHEMBL31306897 | 0.84 | KMT2A (0.66) | KMT2AMEN1LMNAPOLBCASP6 | |
| SCHEMBL1758787 | 0.83 | P2RX1 (0.53) | LMNAP2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL813078 | 0.76 | THRB (0.52) | KMT2AMEN1LMNAP2RX1P2RX3 | |
| SCHEMBL29373003 | 0.76 | LMNA (0.69) | KMT2AMEN1LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675203-B | Preparation method of acridine compound | UNIV CHANGZHOU | 2014-08-13 | — | — | CN | claimed |
| CN-102675203-A | Preparation method of acridine compound | UNIV CHANGZHOU | 2012-09-19 | — | — | CN | claimed |
| US-11158814-B2 | 9,10-dihydro-acridine derivative, and preparation method and use thereof | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD (CN) | 2021-10-26 | — | — | US | disclosed |
| WO-2020056859-A1 | 9,10-DIHYDROACRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 宁波卢米蓝新材料有限公司 | 2020-03-26 | — | — | WO | disclosed |
| WO-2020056860-A1 | 9,10-DIHYDROACRIDINE DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | 宁波卢米蓝新材料有限公司 | 2020-03-26 | — | — | WO | disclosed |
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
| CN-102675203-B | Preparation method of acridine compound | UNIV CHANGZHOU | 2014-08-13 | — | — | CN | disclosed |
| CN-102675203-A | Preparation method of acridine compound | UNIV CHANGZHOU | 2012-09-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11158814-B2 | 9,10-dihydro-acridine derivative, and preparation method and use thereof | GAPVD1, DHX9, DHRS9 | KMT2A 3356/4885MEN1 4288/4885LMNA 535/4885 |
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | DHODH, DHRS9, QDPR | KMT2A 4294/4885MEN1 4830/4885LMNA 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.