Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469642 | 0.94 | HTR6 (0.50) | HTR6HTR2AHTR1AHTR1DHTR1B | |
| SCHEMBL13162969 | 0.82 | HTR6 (0.57) | HTR6HTR2AHTR1DHTR1B | |
| SCHEMBL11370835 | 0.81 | TSHR (0.51) | HTR6HTR1DHTR1B | |
| SCHEMBL13162973 | 0.81 | HTR2A (0.61) | HTR6HTR2AHTR1DHTR1B | |
| SCHEMBL11386609 | 0.79 | HTR1B (0.50) | HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL11370824 | 0.78 | CHRNB4 (0.65) | HTR6HTR2AHTR1AHTR1B | |
| SCHEMBL16347846 | 0.77 | KCNH2 (0.38) | HTR6 | |
| SCHEMBL3764570 | 0.76 | HTR6 (0.54) | HTR6 | |
| SCHEMBL16488227 | 0.76 | HTR6 (0.54) | HTR6 | |
| SCHEMBL8702812 | 0.76 | HRH3 (0.53) | HTR6HTR2AHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | claimed |
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | disclosed |