Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764570 | 1.00 | HTR6 (0.54) | HTR6CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL28216900 | 0.98 | HTR6 (0.55) | HTR6CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL2606119 | 0.95 | ADRA2A (0.53) | HTR6 | |
| SCHEMBL11470450 | 0.93 | ADRA2A (0.51) | HTR6 | |
| Ammonia Solution, Strong SCHEMBL3645001 | 0.93 | ADRA2A (0.51) | HTR6 | |
| SCHEMBL25645586 | 0.93 | ADRA2A (0.51) | HTR6 | |
| Ammonia Solution, Strong SCHEMBL29771408 | 0.87 | HTR1D (0.49) | HTR6 | |
| SCHEMBL13162975 | 0.84 | HTR1D (0.52) | HTR6CHRNB2CHRNA4 | |
| Styrene SCHEMBL28422467 | 0.83 | HTR6 (0.44) | HTR6CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL2691261 | 0.82 | SLC18A2 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-B9 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | OTSUKA PHARMA CO LTD (JP) | 2015-02-18 | — | — | EP | disclosed |