Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 7/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386609 | 0.83 | HTR1B (0.50) | HTR6HTR1DHTR1B | |
| SCHEMBL11375404 | 0.81 | HTR6 (0.56) | HTR6HTR1DHTR1B | |
| SCHEMBL11369857 | 0.78 | CHRNB2 (0.54) | TSHRHTR6CHRNB2CHRNB1CHRNB4 | |
| SCHEMBL8209088 | 0.77 | HTR1B (0.76) | HTR6HTR1DHTR1BGABRPGABRD | |
| SCHEMBL8209086 | 0.77 | HTR1B (0.76) | HTR6HTR1DHTR1BGABRPGABRD | |
| SCHEMBL11372986 | 0.76 | ADRA1A (0.55) | HTR6CHRNB4CHRNA3HTR1DHTR1B | |
| SCHEMBL11469642 | 0.76 | HTR6 (0.50) | HTR6HTR1DHTR1BKDM4EALDH1A1 | |
| SCHEMBL4278447 | 0.73 | CHRNB2 (0.49) | TSHRHTR6CHRNB2KDM4EALDH1A1 | |
| SCHEMBL4813527 | 0.73 | SLC18A2 (0.50) | TSHRKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL11379296 | 0.73 | HTR6 (0.47) | HTR6CHRNB2CHRNB1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | disclosed |