Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361103 | 0.80 | MAPT (0.58) | KMT2AMEN1THRBATMMAPT | |
| SCHEMBL6284986 | 0.80 | KMT2A (0.64) | KMT2AMEN1KIF11PARP10MAPT | |
| SCHEMBL10081937 | 0.79 | KMT2A (0.58) | KMT2AMEN1KIF11PARP10PARP3 | |
| SCHEMBL1883642 | 0.78 | KMT2A (0.47) | KMT2AMEN1KIF11THRBPARP10 | |
| SCHEMBL11382732 | 0.76 | KMT2A (0.66) | KMT2AMEN1PARP10MAPTRAB9A | |
| SCHEMBL10999566 | 0.75 | THRB (0.66) | THRBATMRAB9ACYP3A4ALDH1A1 | |
| SCHEMBL28636841 | 0.74 | PARP10 (0.68) | KMT2AMEN1KIF11PARP10PARP3 | |
| SCHEMBL11903558 | 0.74 | KMT2A (0.44) | KMT2AMEN1KIF11PARP10PARP3 | |
| SCHEMBL17368450 | 0.74 | AKR1C3 (0.56) | KMT2AMEN1KIF11MAPTKDM4E | |
| Carbamic Acid Phenyl Ester SCHEMBL9689374 | 0.73 | MEN1 (0.57) | KMT2AMEN1KIF11ATMPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288364-A | REACTING A 3-/2-HYDROXYIMINOACETYLAMINO/-2-OXOAZETIDINE WITH AN ORGANIC CARBONATE OR ACYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |