Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560751 | 0.84 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1TDP1ICAM1 | |
| SCHEMBL2791741 | 0.83 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1TDP1ICAM1 | |
| SCHEMBL6284986 | 0.82 | KMT2A (0.64) | KMT2AMEN1ALDH1A1KIF11TDP1 | |
| SCHEMBL6398442 | 0.81 | THRB (0.55) | KMT2AMEN1ALDH1A1TDP1MAPT | |
| SCHEMBL10081937 | 0.81 | KMT2A (0.58) | KMT2AMEN1ALDH1A1KIF11PARP10 | |
| SCHEMBL3903145 | 0.81 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1TDP1MAPT | |
| SCHEMBL11768896 | 0.81 | KMT2A (0.49) | KMT2AMEN1ALDH1A1TDP1MAPT | |
| Urea SCHEMBL7262146 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1ICAM1SELEPARP10 | |
| SCHEMBL72231 | 0.79 | MAPT (0.59) | KMT2AMEN1ALDH1A1TDP1MAPT | |
| SCHEMBL7230864 | 0.79 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1TDP1ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101883799-B | High water content silicone hydrogels | BAUSCH & LOMB | 2013-03-27 | — | — | CN | disclosed |
| EP-2397505-A1 | High water content silicone hydrogels | Bausch & Lomb Incorporated (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2222736-B1 | HIGH WATER CONTENT SILICONE HYDROGELS | BAUSCH & LOMB (US) | 2011-09-21 | — | — | EP | disclosed |
| US-7934830-B2 | High water content silicone hydrogels | BAUSCH & LOMB INCORPORATED (US) | 2011-05-03 | — | — | US | disclosed |
| EP-2259141-A1 | PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE | FUJIFILM Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |
| CN-101883799-A | High water content silicone hydrogels | BAUSCH & LOMB | 2010-11-10 | — | — | CN | disclosed |
| EP-2222736-A1 | HIGH WATER CONTENT SILICONE HYDROGELS | Bausch & Lomb Incorporated (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009073321-A1 | HIGH WATER CONTENT SILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20090141234-A1 | High Water Content Silicone Hydrogels | BAUSCH HEALTH AMERICAS, INC. | 2009-06-04 | — | — | US | disclosed |
| EP-1385988-A4 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | SEMOREX INC. | 2004-06-24 | — | — | US | disclosed |
| EP-1385988-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | Semorex Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083708-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| US-5824719-A | HYDROGEL CONTAINING 2-HYDROXYCYCLOHEXYL METHACRYLATE AS STRENGTHENING MONOMER | BAUSCH & LOMB INCORPORATED (US) | 1998-10-20 | — | — | US | disclosed |
| WO-1996040810-A1 | POLYMER COMPOSITIONS FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | disclosed |
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | disclosed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | disclosed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | CD2BP2, HAVCR2, EPCAM | KMT2A 2183/4885MEN1 3655/4885ALDH1A1 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.