Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10231832 | 0.86 | NPSR1 (0.52) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| Lithium Ion SCHEMBL11376401 | 0.81 | MTNR1A (0.42) | MTNR1AMTNR1BCYP1A2CYP2D6PKM | |
| SCHEMBL30363588 | 0.77 | CA12 (0.46) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL19725071 | 0.75 | CA2 (0.44) | MTNR1AMTNR1BCYP1A2PKMALDH1A1 | |
| SCHEMBL15987299 | 0.74 | LMNA (0.45) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL15014295 | 0.74 | NR1I2 (0.43) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL11858961 | 0.73 | MEN1 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL4131267 | 0.73 | SRC (0.40) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL16107474 | 0.73 | SCN4A (0.52) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL8536164 | 0.73 | SCN4A (0.52) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249003-A | Process for polycyclic amines | AKTIEBOLAGET LEO (SE) | 1981-02-03 | — | — | US | disclosed |
| US-4249002-A | Polycyclic amines and intermediates therefor | AKTIEBOLAGET LEO (SE) | 1981-02-03 | — | — | US | disclosed |