SCHEMBL19725071

SCHEMBL19725071

Cc1ccc(S(=O)(=O)OCC(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
GAA P10253 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
CA12 O43570 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
ATM Q13315 1/20 0.42
CA9 Q16790 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CNR2 P34972 2/20 0.41
ALDH1A1 P00352 4/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
MCHR1 Q99705 1/20 0.40
CTSL P07711 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25403099 0.90 ALDH1A1 (0.45) CA2GAABCHEACHECA12
SCHEMBL26286109 0.86 CCR5 (0.44) GAABCHEACHECA12CYP1A2
SCHEMBL4583291 0.84 PKM (0.42) CYP3A4ALDH1A1PKMLMNA
SCHEMBL4756032 0.84 CA2 (0.47) CA2CA7GAABCHEACHE
SCHEMBL17460433 0.84 CA2 (0.47) CA2CA7GAABCHEACHE
SCHEMBL10203187 0.83 GAA (0.50) CA2CA7GAABCHEACHE
SCHEMBL21881540 0.83 ALDH1A1 (0.48) GAABCHEACHECYP1A2CNR2
SCHEMBL23624813 0.82 ALDH1A1 (0.40) CYP1A2CYP3A4L3MBTL1ALDH1A1MEN1
SCHEMBL4432214 0.82 CA12 (0.46) CA2CA7GAABCHEACHE
SCHEMBL21378598 0.82 GAA (0.49) CA2CA7GAABCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257872-A1 CURED-FILM-FORMING COMPOSITION, ALIGNMENT MATERIAL, AND PHASE DIFFERENCE MATERIAL Nissan Chemical Industries, Ltd. (JP) 2017-12-20 EP disclosed