Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703414 | 0.83 | HTT (0.49) | GABRA2GABRB2 | |
| SCHEMBL11366574 | 0.82 | GLP1R (0.42) | GABRA2GABRB2CHEK1DAPK3PRKD3 | |
| SCHEMBL11450932 | 0.80 | CHEK1 (0.48) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL9703937 | 0.80 | KCNJ1 (0.54) | NPC1MAPTALDH1A1LMNA | |
| SCHEMBL11371536 | 0.77 | MAPT (0.48) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL11364737 | 0.77 | CHEK1 (0.46) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL2779501 | 0.76 | MAP3K5 (0.46) | CHEK1MAPTALDH1A1LMNAPDE4A | |
| SCHEMBL11372106 | 0.75 | ALDH1A1 (0.47) | GABRA2CHEK1DAPK3PRKD3MET | |
| SCHEMBL9704323 | 0.74 | GAA (0.53) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL9704126 | 0.74 | POLB (0.45) | NPC1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |