Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376992 | 0.83 | GABRA2 (0.43) | GABRA2GABRB2 | |
| SCHEMBL2779501 | 0.82 | MAP3K5 (0.46) | ADORA3KDM4E | |
| SCHEMBL9704126 | 0.80 | POLB (0.45) | HTTADORA3ALOX15CSF1RTARBP2 | |
| SCHEMBL6377225 | 0.80 | SIRT2 (0.56) | ADORA3ALOX15CSF1R | |
| SCHEMBL9705657 | 0.80 | GLP1R (0.47) | HTTADORA3L3MBTL1ALOX15GLP1R | |
| SCHEMBL9703593 | 0.79 | GRIN1 (0.59) | HTTALOX15HRH4KDM4E | |
| SCHEMBL9703575 | 0.79 | GRIN2D (0.63) | HTTHRH4GLP1R | |
| SCHEMBL9704059 | 0.77 | ADORA3 (0.55) | ADORA3ALOX15CSF1RHRH4GLP1R | |
| SCHEMBL30623229 | 0.77 | ADORA3 (0.55) | ADORA3ALOX15CSF1RHRH4GLP1R | |
| SCHEMBL6080438 | 0.75 | CA12 (0.49) | ADORA3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |