Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386700 | 0.84 | ALOX15 (0.41) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL112781 | 0.71 | PKM (0.52) | CXCR4SMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL140166 | 0.71 | CXCR4 (0.38) | CXCR4RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL6584081 | 0.68 | HPGD (0.45) | CXCR4RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9377414 | 0.68 | HTT (0.47) | SMN1; SMN2LMNAHPGDHTTALDH1A1 | |
| SCHEMBL26032253 | 0.61 | CXCR4 (0.46) | CXCR4RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19296064 | 0.61 | CXCR4 (0.42) | CXCR4RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23921890 | 0.61 | CYP2A13 (0.44) | CXCR4RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL11384756 | 0.61 | L3MBTL1 (0.49) | HTTL3MBTL1MAPT | |
| SCHEMBL27348884 | 0.61 | LMNA (0.41) | CXCR4SMN1; SMN2LMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267337-A | Imidazolemethylphosphonium salts | SK&F LAB CO. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4215217-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4119781-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1978-10-10 | — | — | US | disclosed |