Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23528205 | 0.81 | CHRM2 (0.50) | IDO1AGXTTAAR1 | |
| SCHEMBL23528212 | 0.79 | DAO (0.44) | IDO1ALDH1A1TAAR1SMN1; SMN2KDM4E | |
| SCHEMBL7378242 | 0.77 | CA2 (0.61) | ALDH1A1CYP2D6ATMLMNASMN1; SMN2 | |
| SCHEMBL5377917 | 0.76 | L3MBTL1 (0.51) | LTA4HALDH1A1L3MBTL1SAE1UBA2 | |
| SCHEMBL1859087 | 0.76 | ALDH1A1 (0.47) | LTA4HALDH1A1L3MBTL1CYP2D6LMNA | |
| SCHEMBL1108477 | 0.76 | TAAR1 (0.50) | TAAR1SMN1; SMN2 | |
| SCHEMBL27884 | 0.75 | LTA4H (0.81) | LTA4HIDO1ALDH1A1AGXTTAAR1 | |
| SCHEMBL1425001 | 0.75 | LTA4H (0.81) | LTA4HIDO1ALDH1A1AGXTTAAR1 | |
| SCHEMBL25986524 | 0.75 | LTA4H (0.81) | LTA4HIDO1ALDH1A1AGXTTAAR1 | |
| SCHEMBL28399049 | 0.75 | HRH3 (0.52) | IDO1ALDH1A1TAAR1CYP2D6APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188827-A1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. | 2021-06-24 | — | — | US | disclosed |
| CN-109516978-A | Giantreed alkali derivant and its preparation method and application | 河北工业大学 | 2019-03-26 | — | — | CN | disclosed |
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188827-A1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | ATM, CHEK2, CHEK1 | LTA4H 4678/4885IDO1 3764/4885ALDH1A1 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.